Pre-Confernce Short Courcses

会前短期课程

出席主要会议前，为补充大会之内容，特别举办了3种类之短期课程。

(SC1) Protein Folding, Re-Folding and Aggregation *

2008年4月27日(日) 2:00-5:00pm

Course Instructors:
Theodore W. Randolph, Ph.D., Gillespie Professor, Center for Pharmaceutical Biotechnology Co-Director, University of Colorado (invited)
Carlos N. Pace, Ph.D., Texas A and M University

Protein Folding

Thermodynamic forces that fold proteins (hydrogen bonds
vs. hydrophobic effects)
Kinetics of protein folding
Analytical methods to monitor protein folding

Protein Aggregation

Colloidal and thermodynamic protein stability
Basic formulation strategies
Analytical methods for monitoring protein aggregation

Protein Refolding

Pressure and chaotrope-based refolding methods
Designing screening studies to develop refolding conditions

(SC2) Preclinical Development Antibodies*

2008年4月28日(一) 9:00am - 12:00pm

Course Instructors:
Mohammad Tabrizi, Ph.D., Director, MedImmune
Scott Klalamp, Ph.D., Principle Scientist, MedImmune
Gadi Bornstein, Ph.D., Principle Scientist, AstraZeneca R&D

Affinity Determination: Why Does It Matter, How Can It Impact Your Clinical Dose Selection?
How Do We Measure Affinity and the Challenges
Pharmacokinetics and Pharmacodynamics of Antibodies
Preclinical Development of Antibodies

(SC3) Phage and Yeast Display Library Screening for the Novice *

2008年4月27日(日) 2:00-5:00pm

Presenters:
Jamie Kathleen Scott, M.D., Ph.D., Simon Fraser University
Andrew M. Bradbury, M.B. B.S., Ph.D., Los Alamos National Laboratory
James D. Marks, M.D., Ph.D., University of California, San Francisco

This workshop is meant to bring the novice up to speed on the display technologies covered by the main conference. The workshop will provide an overview of:

Phage display and construction of phage-displayed peptide, scFv and Fab libraries
Yeast display and construction of yeast-displayed scFv and Fab libraries
Screening technologies that are compatible with phage- vs. yeast-display libraries

* 出席本短期课程需要另外申请手续。相关详情敬请参照以下网址：申请首页。

PROBLEM-SOLVING BREAK-OUT SESSIONS

Break-out Sessions are one hour group discussions focused on a particular topic. This is a moderated discussion with brainstorming and interactive problem solving amongst scientists from diverse areas who share a common interest in the discussion topic.

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Insight Pharma Reports
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