ByDr. Peter Wick Empa, Swiss Federal Laboratories for Materials Testing and Research Laboratory for Material - Biology Interaction
09.30
Best Practices on Working with Nanoparticles and Environmental Issues
ByPaul J.A. Borm Centre of Expertise in Life Sciences (CEL) Zuyd University
10.00
The NanoImpactNet Project
Reporting about the progress of NanoImpactNet, the FP7-sponsored network about the Health and Environmental Impact of Nanomaterials
Michael Riediker Institute for Work and Health
10.30
COFFEE BREAK
11.00
Nanomaterials and Workplace Safety
Informations related to the nanoproduction (production, workplace practices) in France.
Dr Eric Gaffet
Directeur de Recherche CNRS / Senior scientist, NanoMaterials Research Group
Partner and Chief Scientific Officer European Academy of Science
11.30
Communicating about Nanotechnology’s Potential Health and Environmental Risks in the Mass Media
Presenting data from a content analysis of coverage of potential health and environmental risks from nanotechnology in 28 U.S. and 10 U.K. newspapers as well as the Associated Press and United Press International wire services from 2000 to 2007. Discussing changes over time in the number of articles presenting information about health and environmental risks.
Authors: Sharon M. Friedman - Science and Environmental Writing Program, Brenda P. Egolf - Center for Social Research
Speaker: Sharon M. Friedman
Professor and Director Lehigh University
12.00
LUNCH
14.00
What “Risk” Means? - Communication Deficiency in the Case of Nanoparticle TiO2 in Sunscreens
Discussing the nanoparticle TiO2 case to illustrate how problems of different origins, which may require different regulatory responses, have been twisted together in current risk discourse and to stress the need for better communication.
Authors: Urjan Jacobs, Kuan-Ting Chi - Department of Biotechnology, Julian Kinderlerer, Professor - University of Cape Town
Speaker: Kuan-Ting Chi Technology University of Delft
14.30
Building Customer and Regulator Confidence while Selling the Nano Inside
Discussing the EC’s nanotechnology strategy, and sharing views on safety and the regulator’s interests, but primarily focusing on NanoCover Scandinavia A/S, a company that is acting to protect people's health and safety by ensuring risks regarding their products are known.
Del Stark
CEO European Nanotechnology Trade Alliance
15.00
Communication Risk to the Public
Reviewing developments in risk communication and applied nanoscience and the special demands associated with public or inexpert audiences. Examining human and environmental toxicology and review preliminary findings from a team of researchers funded by the USA National Science Foundation.
David M. Berube
Professor, Co-ord. PCOST - Department of Communication North Carolina State University
15.30
Nanoproducts Life Cycle Researches Concerning Cottonseed Flax Fibers
Presenting the results of researchers about flax fibers aspects (properties) treated with two different emollients type, with or without ultrasounds for different treatment conditions: temperature, time, hydro module and preparation concentration.
Authors: Prof. PhD. MSc. E. Pintille, Prof. PhD. MSc. V. Blascu, Lecturer PhD, MSc. M. Avadanei, Ass. Prof. L. Hristian
Speaker: M. Avadanei, MSc
Faculty of Textile, Leather and Industrial Management Technical University “Gh. Asachi,” Iasi
16.00
COFFEE BREAK
16.30
Participants: Paul J.A. Borm, Centre of Expertise in Life Sciences (CEL), Zuyd University Dr. Peter Wick, Empa, Swiss Federal Laboratories for Materials Testing and Research Dr Eric Gaffet, AFSSET Nanomaterials Expert Group President, CNRS NanoMaterials Research Group Michael Riediker, Institute of Occupational Health Sciences Dr Daniel Bloch , Medical Advisor, CEA for NanoMaterials
Chairperson:
Dr. Peter Wick
Empa, Swiss Federal Laboratories for Materials Testing and Research Laboratory for Material - Biology Interaction
09.00
Identifying and Mapping Parameters Influencing EHS Risks of Nanomaterials
Through an event-tree analysis, identifying a minimum of 70 parameters which may contribute to environmental, health and safety (EHS) risks of nanomaterials (NM), including NM characteristics, exposure routes, NM aggregates, exposed populations, and exposure concentrations, among others.
Authors: K.D.Grieger, S.F.Hansen, Baun, Kgs. Lyngby.
Speaker: Khara D. Grieger
Department of Environmental Engineering Technical University of Denmark
09.30
Missing Links in the Human Risk Assessment of Nano-Particles – Nano-Silver as a Case Study For human risk assessment sufficient data are needed with respect to exposure as well as the hazard. Presenting an inventory of the data available on nano-silver to identify the pivotal knowledge gaps that have to be filled for a proper risk assessment.
Authors: S.Dekkers, S.Wijnhoven, W.Hagens, Adrienne J.A.M. Sips - Substances and Integrated Risk Assessment
C. Herberts, B.Roszek, R.Geertsma - Centre for Biological Medicines and Medical Technology
Wim H. de Jong, Laboratory for Health Protection Research
Speaker: Susan Deckers National Institute for Public Health and the Environment (RIVM)
10.00
In Vitro Investigation of Nanoparticle and Carbon Nanotube Toxicity and Intracellular Accumulation in A549 Human Pneumocytes
Detailing the response of A549 human pneumocytes after exposure to aluminium oxide or titanium oxide nanoparticles, and to multi-walled carbon nanotubes.
Authors: Simon-Deckers, M. Carrière - Laboratoire Pierre Süe, B. Gouget - AFSSA, Scientific Department
M. Mayne-L’Hermite, N. Herlin-Boime, C. Reynaud -Laboratoire Francis Perrin, CEA-CNRS
Speaker: Marie Carrière Laboratoire Pierre Süe - CEA-CNRS
10.30
COFFEE BREAK
11.00
Pulmonary Toxicity of Carbon Nanotubes - An Update
The current literature on carbon nanotube pulmonary toxicity is becoming more and more extensive. Proposing an update on this literature, with a critical approach on the methodology used.
Sophie Lanone, PhD.,
Faculté de Médecine Xavier Bichat Inserm
11.30
Characterisation of Cytotoxicity and Specific Cellular Responses in Human Cell Lines of Various Lineage to SiO2 Nanoparticles
Presenting the results of the first European multi-centre (NanoInteract FP-6) systematic characterisation of the effects of SiO2 nanoparticles of different size and precisely defined physico-chemical characteristics on cultured human cells of various origin.
Authors: Y.Volkov, B.Mohamed, A.Davies - Trinity College Dublin, A.Elsaesser, G. McKerr, V Howard - University of Ulster, M.Park, W.Jong, M.Stępnik - Netherlands Institute for Public Health and Environment, K.Rzyzyński, J. Byrne - Nofer Institute of Occupational Medicine, I.Montes, A. Lesniak, A.Salvati, I.Lynch, K.Dawson - University College Dublin
Speaker: Dr. Yuri Volkov
Senior Lecturer, Department of Clinical Medicine Trinity College Dublin
12.00
LUNCH
14.00
Effects of Gold Nanoparticle to Human Biological Fluids: Implication for Possible Exposure Risk
Evaluating the effect of gold nanoparticle (AuNP) in human biological fluid, including whole blood, saliva, urine, tear and sperm. Interesting data of AuNP influence to microscopic morphology, biochemical analysis and chemical properties of each fluid secretion are presented.
Authors: A.Sereemaspun, M.D. Ph.D., W. Wiwanitkit, M.D., Rojrit Rojanathanes - Faculty of Science
Speaker : Amornpun Sereemaspun, M.D. Ph.D.,
Faculty of Medicine Chulalongkorn University
14.30
Comparative Study on Acute and Chronic Toxicity of Silica and Titanium Dioxide Nanogels Since most of the drugs are prescribed for a long period of time it is necessary to test not only the acute toxicity of the carrier, but also to evaluate its chronic toxicity. The aim of the presented study is to assess the acute and chronic toxicity of SiO2 and TiO2 xerogels and to compare their effects on animal model systems.
Authors: T.Chervenkov, D.Geroval, V.Gerov, B Galunska - Medical University of Varna
V.Danciu, V.Cosoveanu - University “Babes-Bolyai” Romania
Speaker: Trifon Chervenkov Medical University of Varna
15.00
Effects of Differently Shaped Fine Magnetite Nanoparticles on Human Leukocyte Activity
Discussing a study which aim is to test effects of volume concentrations, particle size and shape of fine magnetite nanoparticles on human leukocyte activities in vitro. The used magnetic particles were spherical, rod-like and chain-like (obtained from the magnetotactic bacteria Magnetotacticum magnetospirillum sp. AMB-1). Authors: Dr.A.Šprincová, M.Koneracká, V.Závišová, A.Džarová, M. Timko, P. Kopčanský -Slovak Academy of Sciences, Martina Dubničková - Faculty of Pharmacy, Comenius University
Speaker: Dr. Adriana Sprincova Institute of Experimental Physics - Slovak Academy of Sciences
15.30
COFFEE BREAK
16.00
Interaction of C70 with a Natural Phenolic Acid Induces Cytotoxicity
Showing how the interaction of fullerene C70 with gallic acid (GA), a phenolic acid ubiquitous in plants, leads to cytotoxicity. Atomistic molecular dynamics simulations reveal the self-assembly of C70 and GA into nano-sized aggregates.
Authors: E. Salonen, I. Vattulainen - Helsinki University of Technology, S. Lin, M. L. Reid, M. Allegood, X.Wang, A. M. Rao and P. C. Ke - Clemson University
Speaker: Emppu Salonen, PhD
Department of Engineering Physics Helsinki University of Technology
16.30
Impact of Physico-Chemical Characteristics of Nanomaterial Interactions with Bacteria in terms of Ecotoxicity or Nanoproducts Lifecycle
Describing biological effects of some metal oxide nanoparticles: TiO2 of various crystalline phases and Al2O3. Focusing on multiwall carbon nanotubes either containing Fe impurities or purified. These objects are studied on the soil bacterium Cupriavidus metallidurans CH34 and on gram negative model Escherichia coli MG1655.
Authors: Simon-Deckers, M. Carrière - Laboratoire Pierre Süe, B. Gouget - AFSSA Scientific Department
M. Mayne-L’Hermite, N. Herlin-Boime, C. Reynaud - Laboratoire Francis Perrin
Speaker : Angélique Simon-Deckers Laboratoire Pierre Süe, CEA-CNRS
17.00
What about the otential Toxicity of Double ｧｫalled Carbon Nanotubes (DWNT) in Amphibian Larvae?
Evaluating the risks of double-walled CNT (DWNT) using the amphibian model larvae (Xenopus laevis) according to the standardized procedure (ISO, 2006)to measure acute toxicity on larvae and genotoxicity as the expression of the clastogenic and/or aneugenic effects of CNT in erythrocytes of the circulating blood (appearance of micronucleated cells). .
Authors: F.Mouchet, E.Pinelli, L.Gauthier - EcoLab UMR 5245, CNRS UPS INPT, École Nationale Supérieure Agronomique de Toulouse
P.Landois, E.Flahaut - CIRIMAT/LCMIE UMR 5085 CNRS UPS INPT, Université Paul Sabatier
Speaker: Dr Emmanuel Flahaut CNRS Researcher
Extremely Rapid Endocytosis and Exocytosis of Nanoparticles by Live Cells
Emphasis is placed on the role of physio-chemical control and in situ characterization of dispersions. This is one of the first efforts to explore how feasible it is to carry out semi-quantitative work. The outcome is hopeful, but indicates the enormous challenge this will require.
Authors: A.Salvati, T.Santos, J.Varela, I. Lynch, K.Dawson - School of Chemistry and Chemical Biology
J.Baugh - UCD Conway Institute for Biomolecular and Biomedical Research
Speaker: Anna Salvati, PhD
Centre for BioNano Interactions University College Dublin
09.30
Interaction between Cerium Oxide Nanoparticles and Bacteria
Investigating the interactions between two bacteria (Synechocystis and E. coli) with cerium oxide nanoparticles in different physico-chemical conditions. The nanoparticles are first carefully characterized to determine their shape, size, surface charge, redox reactivity and solubility.
Authors: O. Zeyons, A. Thill, O. Spalla, P. Jegou, G. Huber
Speaker: Antoine Thill CEA Saclay
10.00
CdTe Nanoparticles Display Tropism to Core-Histones and Histone-Rich Cell Organelles
Quantum dots are capable of a rapid accumulation in the nuclei and nucleoli of human cells in vitro; the precise nature of these processes still remains unknown. Hypothesising that this strong tropism of QDs for the nucleus in a cell could be mediated by the charge-related properties of both nuclear macromolecules and the QDs. Authors: J.Conroy, S.Byrne, Y.Gunko, Y.Rakovich, J.Donegan, A.Davies, D.Kelleher and Y.Volkov
Speaker: Jennifer Conroy, MSc,
Cell Signalling Research - Dept. of Clinical Medicine Trinity College Dublin
10.30
COFFEE BREAK
11.00
Characterisation of Intracellular Compartmentalisation Patterns In Different Cell Types using Size Tuned Quantum Dots
Demonstrating that while the smaller QDs enter the nuclei and locate to the nucleoli in all three cell types, the rate and passage differ depending on cell type. Furthermore as QD size is increased, penetration into the cell is reduced but each cell line had its own cut-off size reflecting cell-type determined nuclear pore size specificity.
Authors: Y.Williams, A.Davies, Y.Volkov - Trinity College Dublin
A.Sukhanova, I. Nabeiv, D.Kelleher - University of Reims
Speaker: Yvonne Williams
Institute of Molecular Medicine Trinity College Dublin
11.30
Categorization and Exposure Classification of Nanomaterials based on the Locations of the “Nano-dimension”
Sugesting that nanomaterials should be categorized depending on the location of the nanoscale structure in the system. This leads to a division of nanomaterials into three main categories: 1. Materials that are nanostructured in the bulk; 2. Materials that have nanostructure on the surface; and 3. Materials that contain nanostructured particles.
Authors: S. Hansen, A.Bauna - Department of Environmental Engineering
B.Larsen - NanoDTU, S.Olsenc - Department of Manufacturing Engineering and Management
Speaker: Steffen Foss Hansen, Ph.D.-student, M. Tech. Soc. Technical University of Denmark
12.00
LUNCH
Chairperson: Barbara Gouget
Project manager Direction scientifique de l'AFSSA
14.00
The Regulation and Governance of Nanotechnology in Developing Countries
Reporting on a 2004 qualitative study undertaken in Thailand and Australia. Thirty-two experts from academic, private and government sectors, as well as representatives from nongovernment organizations, were interviewed about strategies and frameworks for nanotechnology’s implementation in developing countries.
Donald C. Maclurcan
Institute for Nanoscale Technology University of Technology Sydney
14.30
Photo-active Atmospheric Aerosols and Human-health Risk
Discussing results of a lab investigation of photostimulated oxidation of some ecologically significant compounds (CH4, aromatic hydrocarbons, terpenes and CFC) on surface of natural aerosol constituents were taken as example of self-preservation in ecological system.
Anton R. Ivanov
Chemistry Faculty - Organic Department St. Petersburg University
15.00
Teaching Nanostudents Sustainability and Risk Assessment
Describing Engineering Nanoscience, a novel five-year educational program. Besides teaching "pure" nanoscience and -technology, the program prepares the future nanoengineers in dealing with questions concerning risk and sustainability of nanotechnology.
Authors: E.Nilsson, A.Ahrens, K.Deppert, G.Hammarin and J.Lönngren - Faculty of Engineering
Speaker: Elisabeth Nilsson
Education program Engineering Nanoscience Lund University
15.30
NanoPRECAUTION: Information and Training Processes at the CEA
Describing the aims of the NanoCAUTION project which was developed within the FP6 European program Nanosafe2.
Authors: Y.Sicard - Université Joseph Fourier, C.Tardif, H.Jeanson - INSTN-Grenoble
Speaker: Hubert Jeanson
Responsable pédagogique, CEA INSTN-Grenoble
What are the Methodologies to Estimate Toxicity?
Best Practices on Working with Nanoparticles and Environmental Issues
