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蛋白质的精制和回收 1月9日～10日 以使用改革「已实证效果」手法的蛋白质精制技术之主题为重点的此部会，预定进行由专家介绍因应运用生产率高的细胞培养技术衍生出的各种要求能获得的经验等个案研究。此外，透过有关affinity tag、电气泳动法、离心分离、过滤、层析法 （chromatography）、导入卓越作业（operational excellence）计画制程效率化等详细的发表，除公布使精制制程最佳化的方法外，加上以往型的哺乳类系，亦介绍包含因应大肠菌和杆状病毒科(Baculoviridae)、酵母等「特殊」系各种发现系的精制技术。 层析法（chromatography） Capture and Resolution of mAb Charge Variants with Cation Exchangers - Advances and Perspectives Giorgio Carta, Ph.D., Lawrence R. Quarles Professor, Department of Chemical Engineering, University of Virginia Multi-Dimensional Chromatography for Monitoring Quality Attributes of Monoclonal Antibodies in Cell Culture Process Methal Albarghouthi, Ph.D., Senior Scientist, Analytical Biochemistry, MedImmune, LLC
亲和性精制 Ultra Pure Functional Protein Recovery with a Novel High Affinity EF Hand Fusion Protein System David O乫Connell, Ph.D., Senior Scientist, School of Medicine, University College Dublin Quantification of a PEGylated Peptide Drug Candidate in Human Plasma Using Immuno-Affinity Purification with an Anti-PEG Antibody Followed by LC/LC-MS/MS John T. Mehl, Ph.D., Senior Research Chemist, Vaccine Bioprocess Research & Development, Merck Research Laboratories
改革制程 Adaptation of Precipitation Technologies for Improved Downstream Efficiency for Monoclonal Antibody Production Alahari Arunakumari, Ph.D., President, AHA Bioconsultants LLC One-Second Isolation/Immunoprecipitation of Weak Protein Complexes Using a Microfluidic IFAST Device Richard R. Burgess, Ph.D., Professor, Oncology, McArlde Lab for Cancer Research, School of Medicine, University of Wisconsin, Madison Process Development of Primary Recovery Steps for a High Cell Density Product Stream Jessica Molek, Ph.D., Principal Scientist, Downstream Process Development, GlaxoSmithKline Rhobust® Technology – Process Intensification Through Direct Product Capture Spencer Reynolds, Director, Business Development, DSM Biologics
新的蛋白质和精制困难的蛋白质 Differential Filtration Analysis: An Enabling Technology for Membrane Proteins (and Soluble Proteins too!) Michael C. Wiener, Ph.D., Associate Professor, Molecular Physiology and Biological Physics, Center for Membrane Biology, University of Virginia
Expression and Purification of Novel Viral Fusion Proteins for Drug Target Discovery David Bienvenue, Ph.D., Associate Director, VLST Corporation Protease-Based Nanomachines Philip N. Bryan, Professor, Institute for Bioscience and Biotechnology Research, and Department of Bioengineering, University of Maryland 标签技术 Expression and in vivo Ulp1-Mediated Cleavage of SUMO Fusion Proteins Albert J. Courey, Ph.D., Professor, Chemistry & Biochemistry, UCLA The CK-Tag: A Novel Solution for Protein Expression and Purification David Smith, Ph.D., Senior Scientist, Nuffield Department of Clinical Laboratory Sciences, University of Oxford
监视精制中蛋白质的状态 Analysis of Protein Samples by Microfluidics: the Pros and Cons Sabine Suppmann, Ph.D., Protein Expression and Purification Core Facility, Max Planck Institute of Biochemistry |
